Basic Information
VIS ID
TVIS44002376
Fusion event
HTLV-1-TRABD2B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p33
Reference genome
GRCh37/hg19
Start
48458186/47992514 (Hg38)
End
48458186/47992514 (Hg38)
Orient
+
Location type
Intronic
Target gene
TRABD2B
Nearest miRNA
hsa-mir-12136/Upstream/3446962; hsa-mir-101-1/Downstream/3067323;
Nearest TSS
ENST00000473358/Upstream/174448; ENST00000456803/Downstream/1698;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/8042, chr1-CpG: 20/Downstream/1626
Upstream sequence
ACGGATTAAAGACAGGGGCTGCTTAGCCAGAGTTTGTGTGTGCTCCCTTCAGCCTTTGTCGGATTCCTCTGTGGTTGGTGCAAAGAGAGTGTTGAGAGTG
Downstream sequence
ATGGTGGATACCTCACCTCCCCATCCTAAAAAAGATATCGAGGCCAGACCTAGGCCTCTGAACAGAGAGGCCTCCCACAAACCTGCCTCCGAAATGAGAT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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