VISDB Viral Integration Site DataBase

VIS ID

TVIS44002382

Fusion event

HTLV-1-PLCE1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q23.33

Reference genome

Start

End

96086206/94326449 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-5582-5p ; hsa-mir-6768-5p ; hsa-mir-8485 ; hsa-mir-1200 ; hsa-mir-3188 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-4649-3p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-4789-3p ; hsa-mir-6807-5p ; hsa-mir-4653-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-4438 ; hsa-mir-665 ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6134 ; hsa-mir-1827 ; hsa-mir-3192-5p ; hsa-mir-4768-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-7851-3p ; hsa-mir-34b-3p ; hsa-mir-490-3p ; hsa-mir-3611 ; hsa-mir-6126 ; hsa-mir-4493 ; hsa-mir-605-3p ; hsa-mir-4277 ; hsa-mir-584-3p ; hsa-mir-5000-5p ; hsa-mir-328-3p ; hsa-mir-145-3p ; hsa-mir-4307

Nearest miRNA

hsa-mir-107/Upstream/4733622; hsa-mir-1287/Downstream/1737866;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/332005, chr10-CpG: 39/Downstream/36334

Nearest cancer related gene

PLCE1(TSG, No orient, 0)

Upstream sequence

TACATTGAGATCATGTTTCCACATTTAAAGAGCAACTCCTAAAATAACTGATGTCCTATATTACACTCTGCAGTGGTCAAAATTTTAAATATTGTTTTCC

Downstream sequence

ATATCCAGAAGTTAGTATCAAATAAATCATAGGTGTGATGTTATACACACCTCTATAACTTCTGTAATGAGGTGAAATTACACTAAAGCTAGTAAATTGG