Basic Information
VIS ID
TVIS44002409
Fusion event
HTLV-1-LOC105376775 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
77517712/77483815 (Hg38)
End
77517712/77483815 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105376775
Nearest miRNA
hsa-mir-1225/Upstream/614796; hsa-mir-11401/Downstream/3901203;
Nearest TSS
ENST00000527434/Upstream/48701; ENST00000563289/Downstream/106991;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/48638, chr16-CpG: 24/Downstream/238704
Nearby gene
ADAMTS18(-48701) ;
Upstream sequence
ACCAGTGCAATCATTTACAATTGGAAAGGACAGGCTGCTGGAAGACACGGGGCTGTCCTGGCAAGGCAAGCACAACCCAGATCCCTGCCTTTCTCTGTCT
Downstream sequence
TTTCCCATTTCTGCACGGCTTTGACAGTTTTGAGCTGATTCTGGTCATAGCCTGGAGGGAGAGAACATTCATGGCAGCCCCAAGAAGGACAATTAGGTTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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