Basic Information
VIS ID
TVIS44002410
Fusion event
HTLV-1-RAB11FIP3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
511332/461332 (Hg38)
End
511332/461332 (Hg38)
Orient
+
Location type
Intronic
Target gene
RAB11FIP3
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-1277-5p ; hsa-mir-6516-3p ; hsa-mir-190a-3p ; hsa-mir-3607-5p ; hsa-mir-205-3p ; hsa-mir-5011-5p ; hsa-mir-5580-3p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-4789-5p ; hsa-mir-4672 ; hsa-mir-6768-5p
Nearest miRNA
hsa-mir-6859-4/Upstream/444213; hsa-mir-11401/Downstream/73984;
Nearest TSS
ENST00000527434/Upstream/34953; ENST00000483002/Downstream/13518;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/34517, chr16-CpG: 16/Downstream/21135
Upstream sequence
ctcctgctgatctgacaggaggggagctcaggcggtaatgctccctcacctcctgctgtgcttccccgttcccagcaggccacacaccagatctctccca
Downstream sequence
gtccgaggtccagggttggggacccctgCTGTAAAGGCTTAGGGTAACCTAGTCTCATTTGGCAATTACAGGTGAAGGACTTAACTAAGTACTTGGATCC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate