Basic Information
VIS ID
TVIS44002413
Fusion event
HTLV-1-LOC102725101 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
32063736/32052415 (Hg38)
End
32063736/32052415 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102725101
Nearest miRNA
hsa-mir-1225/Upstream/1158430; hsa-mir-11401/Downstream/2111163;
Nearest TSS
ENST00000527434/Upstream/17562; ENST00000568138/Downstream/6669;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/70186, chr16-CpG: 178/Downstream/31926
Nearby gene
HERC2P4(-117628) ;
Upstream sequence
CAAACCTCTCTGCAGAATGCTTGGGGGAAATCAGCTGCGGGGGGCACACAGGACCCACTGATCAGAGTCATCCCCAGAGGCAAGTTGCAGATGGAGGCTG
Downstream sequence
GTTTCCTGTCAGGATGTGGGACTTCATCTTTTTAGAGTTTCTCTAGGGAATCTCTCTAAGTTCAGAATTCTGTGCTTACCAATGTCATCTCTACATATTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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