Basic Information
VIS ID
TVIS44002419
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
41069744/43489779 (Hg38)
End
41069744/43489779 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/3813000; hsa-mir-122/Downstream/1480303;
Nearest TSS
ENST00000575820/Upstream/212129; ENST00000591940/Downstream/1041876;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/3647914, chr18-CpG: 180/Downstream/1189239
Nearby gene
SYT4(-212129) ;
Upstream sequence
AGAGCACAAACACACCATAAGAAAAGAAAAGAACTGCTTTTGGCAGATAGGATAAGGAGAAGCCCTAAGATTTTAACTCTAGTCTGGAAAGCAGGTCTCA
Downstream sequence
GGGAAGGCATGTCTGAAGTCCAGAAGACCAGGGGAAACCTGAATGCAGAAAGTGCAgctggttcactatgtcgtgaaatacaacaaccagggaacaccct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate