Basic Information
VIS ID
TVIS44002421
Fusion event
HTLV-1-LOC107985164 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
53670041/56002810 (Hg38)
End
53670041/56002810 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA18B
Target gene
LOC107985164
Nearest miRNA
hsa-mir-1-2/Upstream/523512; hsa-mir-122/Downstream/2448264;
Nearest TSS
ENST00000575820/Upstream/4471; ENST00000589983/Downstream/39325;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/222199, chr18-CpG: 57/Downstream/635378
Nearby gene
LINC01539(No orient, 80546)
Upstream sequence
ttgtatttttagtagagacagggtttcaccatgttggtcaggctggtcttgaactcctgacctcaggtgatctgcccgcctaggcctcccaaaatgttgg
Downstream sequence
gactatggccatgagccaccgcaccggcTGGCCCTACTTTCTATTCCCAAAATGGATTCCCTTTCTACTCCAAAAATGGCCCTACATGGGCCCACTCCAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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