Basic Information
VIS ID
TVIS44002428
Fusion event
HTLV-1-LOC102724805 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
88969060/88669542 (Hg38)
End
88969060/88669542 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2L
Target gene
LOC102724805
Nearest miRNA
hsa-mir-1285-2/Upstream/586943; hsa-mir-10b/Downstream/142828;
Nearest TSS
ENST00000437798/Upstream/41371; ENST00000283646/Downstream/22102;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/41765, chr2-CpG: 65/Downstream/21909
Nearby gene
RPIA(+22116) ;
Upstream sequence
AAACAAATACTTTTTGCAATACCTTGGATGACATTATGTAGGAGGATTTGTTAGAAGAATACCTTGCAAGacacacacacacacacacacCCTAAAGGCA
Downstream sequence
AAAGTGACGCACATACTGAACATTTAATATGGTTTTGACTCCAAATCCTTTGTACAGCACCTGTTGTCTGAGCTTGATAAAGATTTGATAAACTGTTGAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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