Basic Information
VIS ID
TVIS44002459
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
GRCh37/hg19
Start
88977970/88268251 (Hg38)
End
88977970/88268251 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6G
Nearest miRNA
hsa-mir-10398/Upstream/9728942; hsa-mir-1202/Downstream/2044491;
Nearest TSS
ENST00000381078/Upstream/101892; ENST00000354922/Downstream/152782;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/100521, chr6-CpG: 60/Downstream/694914
Nearby gene
CNR1(-102203) ;
Upstream sequence
TTCAATAGTTTTGATCATTCTTTCATGATGAGGTAGCACATTAATTGCTTCTGGAAATGTGATGCTTTTAATGTAGTGGTTTTCGAATGTTTTGCTTTGG
Downstream sequence
GAATCATTTTATTAAAGGTTAAAAACAAAACAATGAGCACATGTCCCACTGCCACCACCAACTCCTACTTCCTCTGCCTTTGGCCCTTCTTACCAAAACT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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