Basic Information
VIS ID
TVIS44002475
Fusion event
HTLV-1-ADGRB1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
143568983/142487622 (Hg38)
End
143568983/142487622 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
ADGRB1
Nearest miRNA
hsa-mir-1204/Upstream/311204; hsa-mir-10400/Downstream/1245461;
Nearest TSS
ENST00000518652/Upstream/8502; ENST00000518812/Downstream/55879;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/10159, chr8-CpG: 15/Downstream/11786
Upstream sequence
TGCCCTCTCCTCCTCTCCCTGCCGCATCTTGGGCTGCATTCTTGAGGCTCCACTGGGGCCTGTGAGGGCTGAGGCCACGGCCCCAGGGCCAGGTTCCCCC
Downstream sequence
AGAACAGTGGGTCCCTGTCAGCACCTGCTTCCACCCCAGCGGCACTTCCCCAAACTCTCTTCCCGTCCAGTTGCCCCAAACCTGCTGCCTCGTCCCCACG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate