Basic Information
VIS ID
TVIS44002483
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p11.4
Reference genome
GRCh37/hg19
Start
42074918/42215665 (Hg38)
End
42074918/42215665 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1587/Upstream/2378052; hsa-let-7f-2/Downstream/3530492;
Nearest TSS
ENST00000429181/Upstream/160829; ENST00000411879/Downstream/36794;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/291660, chrX-CpG: 34/Downstream/562092
Nearby gene
CASK(-292631) ;
Upstream sequence
GTAAGATTCCCCAGCTTCAAAAATAAGGTCATCTGTTAGTAATTCTCTGCTTCAATTGGCAAATGACCTACCTACCAAGGACATGCAGTTGAAATGAGCA
Downstream sequence
TGTGCCTCCTCCTGAGAAGGTTAAAATTTCCTTCTGCCTGTGACCTTAGGAGATAGCTCATCATGGTGTGTCCATTTACCTCATTGAGGTAAATGGAGTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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