Basic Information
VIS ID
TVIS44002486
Fusion event
HTLV-1-SYTL5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p11.4
Reference genome
GRCh37/hg19
Start
37921020/38061767 (Hg38)
End
37921020/38061767 (Hg38)
Orient
+
Location type
Intronic
Target gene
SYTL5
Nearest miRNA
hsa-mir-23c/Upstream/37781; hsa-let-7f-2/Downstream/1599449;
Nearest TSS
ENST00000429181/Upstream/28233; ENST00000423919/Downstream/92814;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/155763, chrX-CpG: 48/Downstream/158671
Upstream sequence
GCTGAGCAGGCCCTGACATTTTCTCCAATCCCTTCTGATTCCAACAAGTTGGCTATTGTAAGCCTAGTTTTTAAACTCTATAAAAAACATGATAAAAGGG
Downstream sequence
ACCTTGACACAGCCAGTTAATTCATTTTTCTATCTTAATAATACCTACAAAATTCCACATTGTTATGTTAGCTGAGGCAGTTGCAGTCCAACACAAAGAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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