Basic Information
VIS ID
TVIS44002491
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
131996937/130198673 (Hg38)
End
131996937/130198673 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/355299; hsa-mir-202/Downstream/763915;
Nearest TSS
ENST00000439456/Upstream/18488; ENST00000439421/Downstream/240394;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/7605, chr10-CpG: 24/Downstream/4294
Nearby gene
GLRX3(+18291) ;
Upstream sequence
aaaaaaaaaaaaaaagaaTTTTGCTGAGAACGTGTTTGGCTACCTGTGCGAAAATGTGAGTAACTGATTTCAAATACAGCTAAAAATACAAGTTGTAAAA
Downstream sequence
AAGACACCAAATTTTTGACCAGCAGAATTTTTTTTTCCCTCAGGAGCTCTTGGATCTCTTTGAGAAATGTATTCTGTTTCATCCTTAAGCTACAGATACG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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