Basic Information
VIS ID
TVIS44002510
Fusion event
HTLV-1-LOC105377657 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
55671681/54805515 (Hg38)
End
55671681/54805515 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA4B
Target gene
LOC105377657
Nearest miRNA
hsa-mir-12113/Upstream/2092768; hsa-mir-1243/Downstream/6117104;
Nearest TSS
ENST00000502981/Upstream/76223; ENST00000514413/Downstream/39887;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/146385, chr4-CpG: 64/Downstream/319720
Nearby gene
KIT(+64800) ;
Upstream sequence
cagtgaacacagaacactcctacattgctggtgggaatgtaaactagtaaaaccactatggaaaacagtgtggagattccttaactaaaagtaaaactaa
Downstream sequence
catttgattcaacaattccaccactgggtacctacccagagggaatgatgtcgttatatgaaaaaggtacttggacatatatttatagcagcacaatttg
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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