Basic Information
VIS ID
TVIS44002521
Fusion event
HTLV-1-chrY integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
8385173/8517132 (Hg38)
End
8385173/8517132 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-2/Upstream/3910904; hsa-mir-12120/Downstream/4962045;
Nearest TSS
ENST00000430575/Upstream/712208; ENST00000413486/Downstream/121162;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/236963, chrY-CpG: 24/Downstream/819394
Nearby gene
TTTY18(-166238) ;
Upstream sequence
GTTCCGTGGCTGGTATGAGCATGCAGACTCCCCTTCCTCCAAGGACTTTCCCAGGGAAACATACCCTTCAACTCTCTGCTGTGCAAGAAGGGTCCTTGGC
Downstream sequence
ACCGCTATTCTCCCTTGTGCATGCTGAGCTTGGCCCGCAGTCCCTACCACATGCTCTCAGGGCACCCGCAAACAAGCTGCCCTCCTATCTGCGGGAGTCT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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