Basic Information
VIS ID
TVIS44002526
Fusion event
HTLV-1-LOC105371881 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
67996385/70000244 (Hg38)
End
67996385/70000244 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105371881
Nearest miRNA
hsa-mir-10226/Upstream/900588; hsa-mir-1250/Downstream/4748369;
Nearest TSS
ENST00000595228/Upstream/38482; ENST00000588782/Downstream/51033;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/672548, chr17-CpG: 87/Downstream/168528
Nearby gene
LINC01497(No orient, 16700)
Upstream sequence
AGATATTGTGGAGAAGAGACTGAGGAAAAAAATGAACATTATTCTCAGTAAGAGCTGGATGAACTTATAGCCTGAAGTGACTCTGGTATAGTCTCATCTT
Downstream sequence
AAATAGGGAAATATATACATAAACATCTTAAAATATTACCAGTGACCAGCATTATTTGTATTTCCAGAGAATTTATGGTTAAAATTAGGATCAAAGAATT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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