VISDB Viral Integration Site DataBase

VIS ID

TVIS44002532

Fusion event

HTLV-1-AAK1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

p13.3

Reference genome

Start

End

69811149/69584017 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA2S ; FRA2E

Target gene

miRNAs that regulate target gene

hsa-mir-3663-3p ; hsa-mir-7848-3p ; hsa-mir-155-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-622 ; hsa-mir-148a-5p ; hsa-mir-3942-3p ; hsa-mir-5100 ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-6731-3p ; hsa-mir-892c-5p ; hsa-mir-1276 ; hsa-mir-6839-3p ; hsa-mir-3679-3p ; hsa-mir-6826-3p ; hsa-mir-629-5p ; hsa-mir-4261 ; hsa-mir-875-3p ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-4308 ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-587 ; hsa-mir-145-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-4272 ; hsa-mir-580-5p ; hsa-mir-3662 ; hsa-mir-377-3p ; hsa-mir-216b-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3671 ; hsa-mir-372-5p ; hsa-mir-888-5p ; hsa-mir-8070 ; hsa-mir-6759-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-3653-5p ; hsa-mir-371a-5p ; hsa-mir-4314 ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-6508-3p ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4746-3p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-764 ; hsa-mir-500a-5p ; hsa-mir-2355-5p ; hsa-mir-6793-3p ; hsa-mir-889-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6513-3p ; hsa-mir-6878-3p ; hsa-mir-378a-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-6778-3p ; hsa-mir-212-5p ; hsa-mir-1224-3p ; hsa-mir-6813-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-3065-5p ; hsa-mir-3529-3p ; hsa-mir-3978 ; hsa-mir-497-3p ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-548t-3p ; hsa-mir-6776-3p

Nearest miRNA

hsa-mir-1301/Upstream/480262; hsa-mir-10b/Downstream/668901;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/146333, chr2-CpG: 136/Downstream/58837

Upstream sequence

GAATGGAAAAAAAATGTCTTAGTTGTCTCTCCAGGTAAACCTGGGGTATCAGCCATGTTCTGATAGCCAGCTTCACCTGACCACCCTTCCCTAATAAGGA

Downstream sequence

ACCTCTTTTACAGAATAATTAACCTTCTACACTGCTCTCCAAGCTAATGGGGAACATCTGCTTAGGAGCCCTCCATGGCTGCTTCATCTCCCTCCCCGCA