Basic Information
VIS ID
TVIS44002541
Fusion event
HTLV-1-LRRC4C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p12
Reference genome
GRCh37/hg19
Start
40150128/40128578 (Hg38)
End
40150128/40128578 (Hg38)
Orient
+
Location type
Intronic
Target gene
LRRC4C
Nearest miRNA
hsa-mir-1343/Upstream/4118374; hsa-let-7a-2/Downstream/3431078;
Nearest TSS
ENST00000527297/Upstream/1479720; ENST00000524493/Downstream/113305;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/3618111, chr11-CpG: 49/Downstream/3183311
Upstream sequence
ttaactgcattatgacaattcattctttttagagtatttagattgaatttttaaattaaaaatatgttcatgctattcttttagttgaaacacccctatt
Downstream sequence
agctccatacctttttagaacaaaatgcaaactgctttggtctccaagactcagcctgacctctgtctgcttctcccacttctcaactttttcttactcc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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