Basic Information
VIS ID
TVIS44002542
Fusion event
HTLV-1-LOC100130987 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
67112075/67344604 (Hg38)
End
67112075/67344604 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA11H
Target gene
LOC100130987
Nearest miRNA
hsa-mir-10392/Upstream/298896; hsa-let-7a-2/Downstream/145641;
Nearest TSS
ENST00000527297/Upstream/26733; ENST00000613900/Downstream/8474;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/26262, chr11-CpG: 26/Downstream/8781
Upstream sequence
TTGATGCCTTCCTCACTGAGAAGGCCTTAGGAGAAGATGGCTCCTGCCATCAAGGCCACACAACTCCTATGGAGAAGTGACTTAGAGCCCAAAGAGTTGC
Downstream sequence
ATTTACAACTCTCACACAAATGATTCTCACGGGCTAGACAGGATCAAAAAGTACGTGTGAGTAggctgggcacagtggctcacacctgtaatcccagcac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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