Basic Information
VIS ID
TVIS44002549
Fusion event
HTLV-1-ARHGAP24 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.23
Reference genome
GRCh37/hg19
Start
86657843/85736690 (Hg38)
End
86657843/85736690 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGAP24
Nearest miRNA
hsa-mir-12113/Upstream/14157; hsa-mir-1243/Downstream/805792;
Nearest TSS
ENST00000502981/Upstream/132537; ENST00000503917/Downstream/42016;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/260874, chr4-CpG: 77/Downstream/857340
Upstream sequence
TTATCATCCAATAAACATCAAGTAGAGGTGGAATTCTGCTGAACACTCAAGGAACACCGATCAAGTCCATTATTGAAGCAATCGAGTACTTACAAAACTA
Downstream sequence
GTAAGTAGGTAGAGGAGAAGAGATTTTTGTTTCTGCTGTATCTCTTAGGCAATTTCTCTAATTCTTGTGGCATCCACTTCCTCAACAGTTAAGTGAATGT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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