Basic Information
VIS ID
TVIS44002571
Fusion event
HTLV-1-LOC105372462 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
55932648/55421281 (Hg38)
End
55932648/55421281 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
LOC105372462
Nearest miRNA
hsa-let-7e/Upstream/33039; hsa-mir-10394/Downstream/2913407;
Nearest TSS
ENST00000633603/Upstream/13504; ENST00000591164/Downstream/21056;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/12833, chr19-CpG: 80/Downstream/11802
Nearby gene
SHISA7(-7457) ;
Upstream sequence
ctgaggcaggaggatggcttgagcccaggagtttaagaccagcctgggcaacacaatgagacccccatctctattaaaaaaaaagcttaaaaattagcca
Downstream sequence
ggcatgttggtgtgcacctgtaatcccagctattcaggaggctgaggtgagaggatcccttgtgctcagaaggccaaggctgcagtgagtctcgttggtg
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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