Basic Information
VIS ID
TVIS44002578
Fusion event
HTLV-1-POLRMTP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
60215279/62137918 (Hg38)
End
60215279/62137918 (Hg38)
Orient
-
Location type
Intronic
Target gene
POLRMTP1
Nearest miRNA
hsa-mir-10226/Upstream/2094813; hsa-mir-1250/Downstream/806297;
Nearest TSS
ENST00000595228/Upstream/72636; ENST00000635817/Downstream/206023;
Nearest CpG islands
chr17-CpG: 175/Target, None/Upstream, None/Downstream
Nearby gene
MED13(-72636) ;
Upstream sequence
GGGCTCCAGGTTGACGGAGGCGGCGCCCACGCTGTCGCGGCCCAGAGCAGCATAATGCTGCAGGCCGTTGCAAGAGCCGTCCTGATGGACGGGGAGGTGG
Downstream sequence
GAGACATAGGCGGCAGGGTCGGAGGCGCGCACAGTGTTCGCCACCTCCATACAGCAGGCCAGCGTCTGCCAGGGTTCCTCCGCGCCCATCCACCACTTTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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