Basic Information
VIS ID
TVIS44002620
Fusion event
HTLV-1-LCN15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
139658607/136764155 (Hg38)
End
139658607/136764155 (Hg38)
Orient
+
Location type
Intronic
Target gene
LCN15
Nearest miRNA
hsa-let-7a-1/Upstream/17185; hsa-mir-3621/Downstream/66802;
Nearest TSS
ENST00000422679/Upstream/5612; ENST00000484854/Downstream/309;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/3453, chr9-CpG: 14/Downstream/5249
Upstream sequence
GCCCTCCTTGCCCAGGGACCCAGGGGACAACTCAGAAGTCACACAGCAAGGGGTCTCGGAGTGGCCATGTCTTGGGTGTGAGCTGAGCCCAGGTGGACAG
Downstream sequence
GAACTCatcttgggtaggtcacagtgcaactgtgagcctcagttcccagctgtgaagtgggtgcagtaatgatccattcacaggttggtttaggattaag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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