Basic Information
VIS ID
TVIS44002633
Fusion event
HTLV-1-LINC01599 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
50505615/50038897 (Hg38)
End
50505615/50038897 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC01599
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-208a/Upstream/72386; hsa-mir-1185-1/Downstream/260958;
Nearest TSS
ENST00000550708/Upstream/27508; ENST00000426751/Downstream/191;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/35196, chr14-CpG: 60/Downstream/77355
Upstream sequence
GTGGGGATTTTCTGGGACAGGGCGGAGATGATGAGATGCTGGAGTTGCATGAGCTGGTCATTACAGTCAAGACTTGTGAACCAGTTGTGAAACCCttggt
Downstream sequence
aacctgaaatctgctatggtgggagtatttacactacagaaattggccaatgctgcaaatcagggtttctttcttttttcagtgagacactgcaccagca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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