Basic Information
VIS ID
TVIS44002640
Fusion event
HTLV-1-ZNF536 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q12
Reference genome
GRCh37/hg19
Start
31053279/30562372 (Hg38)
End
31053279/30562372 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNF536
Nearest miRNA
hsa-mir-10395/Upstream/10163018; hsa-let-7e/Downstream/4560328;
Nearest TSS
ENST00000633603/Upstream/13026; ENST00000585364/Downstream/106275;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/111098, chr19-CpG: 46/Downstream/157238
Nearby gene
ZNF536(+4313) ;
Upstream sequence
TAGGGCCCCTGGGATATGTTCTGGTTTCCCACAAGCATAAGAGCATGCAGGCTTTCTATTTGGGCAAGGCCATCTGCCATTCCAGTGCACGGGCATATGA
Downstream sequence
AACTTGCCTTATCCTGAAGATATTTCTGTTAAATTAGAAGAAGACCATTGAGGATTTTCTTTTAATTGTGGAAGTCTGTTAAAATAGCAAAAGAAAAGAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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