Basic Information
VIS ID
TVIS44002642
Fusion event
HTLV-1-DPY30 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
32245615/32020546 (Hg38)
End
32245615/32020546 (Hg38)
Orient
-
Location type
Intronic
Target gene
DPY30
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-1301/Upstream/4024097; hsa-mir-10b/Downstream/511607;
Nearest TSS
ENST00000437798/Upstream/7485; ENST00000645400/Downstream/3211;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/9516, chr2-CpG: 24/Downstream/19187
Nearby gene
DPY30(-3357) ;
Upstream sequence
ggttgcagtgagctatgaccatgccattgcactccaacctgggtgacagagcaagacctcatctctaaataaataaaGTATTAAAATTAAAATTAAACCT
Downstream sequence
ACCCCaaattttgaggggtgaggaatatgtttatggccttgatggtagttatggtttcagtgatctatagttatctccaaagtaatcaagttgtatatat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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