Basic Information
VIS ID
TVIS44002654
Fusion event
HTLV-1-TRIM61 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
165892938/164971786 (Hg38)
End
165892938/164971786 (Hg38)
Orient
-
Location type
Intronic
Target gene
TRIM61
Nearest miRNA
hsa-mir-12113/Upstream/1878158; hsa-mir-1305/Downstream/414456;
Nearest TSS
ENST00000502981/Upstream/14838; ENST00000507119/Downstream/5882;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/14492, chr4-CpG: 80/Downstream/140430
Upstream sequence
tttcaatctttctgtaagtttgacactttcaaaacaaaaGTGAGGCAGAAAAACTTCCTGGCTTGCTTTCAAGACACCCACAGGTACCCGATTTTAAGCA
Downstream sequence
AGTCAAATTCCTCCATCAAAGCTTGAAAGCCACCTAACCATCAATACAGTATTTTTTCCCCTTCACCTCCTTTCCCTAGACACTTTCTTAACTCTTCTTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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