Basic Information
VIS ID
TVIS44002667
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
GRCh37/hg19
Start
112215618/111894415 (Hg38)
End
112215618/111894415 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6F
Nearest miRNA
hsa-mir-10398/Upstream/5110195; hsa-mir-1202/Downstream/7174632;
Nearest TSS
ENST00000381078/Upstream/20963; ENST00000483439/Downstream/7436;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/20764, chr6-CpG: 49/Downstream/192788
Nearby gene
FYN(-20963) ;
Nearest cancer related gene
FYN(OG, -20963) ;
Upstream sequence
gcacaaagaacacctgctctaaggaaacttgtttaactttcctgcccaggattcctccaacttctatcatgctggaaccttctttcacagaacactaatg
Downstream sequence
ttctgaggagcgagtgtactatgaagcacatttggggaaatgctgCCCCAAATATTTAGCAAAGAGAGCCTTTCAGGAAGTGAAGCAGATGATTGGAATT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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