Basic Information
VIS ID
TVIS44002668
Fusion event
HTLV-1-COL28A1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
7559607/7519976 (Hg38)
End
7559607/7519976 (Hg38)
Orient
-
Location type
Intronic
Target gene
COL28A1
Nearest miRNA
hsa-mir-339/Upstream/452931; hsa-mir-10399/Downstream/10607244;
Nearest TSS
ENST00000635602/Upstream/82541; ENST00000433056/Downstream/97;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/336633, chr7-CpG: 85/Downstream/46765
Upstream sequence
ATTTGTGAATTCAAGCTAATAGAAATAAGATAGATAATATAGGAAGTGGAAATCCTGTATTCTTCACAAAAGTTGTCACATTTTTGCCATATACTACAAT
Downstream sequence
GCTTTTTATTTTTAAAATTGTTGTTTTAAAAAAAAAGTCTAGAAGGAGATACGCTGGTTTAAAGAAAAGCTGTTTATTCATTTACCGGGTTTCCTTTTGG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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