VISDB Viral Integration Site DataBase

VIS ID

TVIS44002680

Fusion event

HTLV-1-LCOR integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q24.1

Reference genome

Start

End

98737148/96977391 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-615-3p ; hsa-mir-425-5p ; hsa-mir-335-5p ; hsa-mir-103a-3p ; hsa-mir-101-3p ; hsa-mir-877-3p ; hsa-mir-193b-3p ; hsa-mir-27b-3p ; hsa-mir-17-5p ; hsa-mir-570-5p ; hsa-mir-548ag ; hsa-mir-548ai ; hsa-mir-548ba ; hsa-mir-548t-5p ; hsa-mir-4282 ; hsa-mir-548az-5p ; hsa-mir-192-3p ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-4694-5p ; hsa-mir-574-5p ; hsa-mir-23a-5p ; hsa-mir-23b-5p ; hsa-mir-1266-3p ; hsa-mir-3117-5p ; hsa-mir-3613-5p ; hsa-mir-7152-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-203a-3p ; hsa-mir-30b-5p ; hsa-mir-144-3p ; hsa-mir-30e-5p ; hsa-mir-3607-3p ; hsa-let-7a-3p ; hsa-let-7b-3p ; hsa-let-7f-1-3p ; hsa-mir-98-3p ; hsa-mir-139-5p ; hsa-mir-381-3p ; hsa-mir-539-5p ; hsa-mir-300 ; hsa-mir-4666a-3p ; hsa-let-7f-2-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-107 ; hsa-mir-4310 ; hsa-mir-6755-5p ; hsa-mir-7157-5p ; hsa-mir-6124 ; hsa-mir-4255 ; hsa-mir-138-2-3p ; hsa-mir-5197-5p ; hsa-mir-6516-5p ; hsa-mir-5589-3p ; hsa-mir-619-3p ; hsa-mir-6765-3p ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-7705 ; hsa-mir-124-5p ; hsa-mir-142-3p ; hsa-mir-3973 ; hsa-mir-1827 ; hsa-mir-5572 ; hsa-mir-4260 ; hsa-mir-450a-2-3p ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-6810-5p ; hsa-mir-3150a-3p ; hsa-mir-2110 ; hsa-mir-5681b ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-5002-5p ; hsa-mir-6854-5p ; hsa-mir-205-5p ; hsa-mir-4789-5p ; hsa-mir-7849-3p ; hsa-mir-7844-5p ; hsa-mir-935 ; hsa-mir-455-3p ; hsa-mir-363-3p ; hsa-mir-25-3p ; hsa-mir-367-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-32-5p ; hsa-mir-3147 ; hsa-mir-4425 ; hsa-mir-4668-5p ; hsa-mir-4781-3p ; hsa-mir-5680 ; hsa-mir-297 ; hsa-mir-675-3p ; hsa-mir-3145-3p ; hsa-mir-101-5p ; hsa-mir-4423-3p ; hsa-mir-6806-5p ; hsa-mir-302a-5p ; hsa-mir-3622a-5p ; hsa-mir-5582-5p ; hsa-mir-548g-3p ; hsa-mir-548av-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3120-3p ; hsa-mir-548m ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-6744-5p ; hsa-mir-7161-5p ; hsa-mir-8087 ; hsa-mir-548u ; hsa-mir-424-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-5088-3p ; hsa-mir-4667-3p ; hsa-mir-6756-3p ; hsa-mir-1470 ; hsa-mir-3127-3p ; hsa-mir-6800-3p ; hsa-mir-3923 ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-767-5p ; hsa-mir-587 ; hsa-mir-6852-3p ; hsa-mir-3909 ; hsa-mir-3124-3p ; hsa-mir-6884-3p ; hsa-mir-513b-3p ; hsa-mir-1252-3p ; hsa-mir-3149 ; hsa-mir-6732-5p ; hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-338-3p ; hsa-mir-4530 ; hsa-mir-646 ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-7856-5p

Nearest miRNA

hsa-mir-107/Upstream/148627; hsa-mir-1287/Downstream/898422;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/143875, chr10-CpG: 27/Downstream/65917

Upstream sequence

ACTGCTAAGATCAGCCACTGTTTGGAAGCCAGTAAGAAAGAAGATTTAATACAATACAGGCCACCACTGTAGTTTTTAGGAAGTCAGACTTAGTTAATTG

Downstream sequence

AGTTGCCCCTCAAACTATTAATCTAATTCAGTCTAGTATAATAAAAATAATAGCCAGACTTCAGTAATAGTCCATATGGTAATGATCCCAAGTATCAGGA