Basic Information
VIS ID
TVIS44002689
Fusion event
HTLV-1-NTAN1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
15141813/15047956 (Hg38)
End
15141813/15047956 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA16A
Target gene
NTAN1
miRNAs that regulate target gene
hsa-mir-100-5p
Nearest miRNA
hsa-mir-1225/Upstream/37559; hsa-mir-11401/Downstream/86119;
Nearest TSS
ENST00000527434/Upstream/462; ENST00000552015/Downstream/7831;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/57649, chr16-CpG: 80/Downstream/7391
Upstream sequence
GTGTGCCTCAGGACCACAATGTGACAAGTAGTGGCATCATCAGAACCCAGAATGGAGATGGAGCCTGTTTAAAAAAGAAATAAAATAAAATATCCAATAG
Downstream sequence
CCTTTTGGGATAACGCCCAATTCACTGCTTCCTAACCTACCATCCTTTGGGGAGGTCACTGCAAGCTCTCTTTGCTGAACATACAGAAGGCCCTGGGGTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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