Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene25389512256920262613768825747894257492082572915125729474257629352576323825763600
Basic Information
VIS ID
TVIS44002690
Fusion event
HTLV-1-HS3ST4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
25774921/25763600 (Hg38)
End
25774921/25763600 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA16E
Target gene
HS3ST4
Nearest miRNA
hsa-mir-1225/Upstream/1560369; hsa-mir-11401/Downstream/261637;
Nearest TSS
ENST00000527434/Upstream/71574; ENST00000475436/Downstream/123146;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/70290, chr16-CpG: 34/Downstream/1346090
Upstream sequence
TACCAACGATCACCAGGCACTGTGATGGGTGCTGGGATGTAATTGTGTGCAGTAATAGACACTGTCTAAGTTAAATATCTGAAGGAAGAAGAAGGGTTAG
Downstream sequence
CCATGTGAAGTGTGGCTAGGGGAGAGACATGGAATATTGCAGGCAGAGGGAAGGAATATGTGCGGGGCTCTGGAGCATGCATTCAGCTGGAAAGAAATTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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