Basic Information
VIS ID
TVIS44002695
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q13
Reference genome
GRCh37/hg19
Start
112329620/111572043 (Hg38)
End
112329620/111572043 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2B
Nearest miRNA
hsa-mir-1285-2/Upstream/250957; hsa-mir-10b/Downstream/199018;
Nearest TSS
ENST00000437798/Upstream/48667; ENST00000426124/Downstream/35798;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/347285, chr2-CpG: 63/Downstream/311717
Nearby gene
MIR4435-2HG(No orient, 76928)
Upstream sequence
CCCACCACGTGGAACAGCAGGTGGAGGGTGGAAGTTGGCTCTCCTACTGCTGACCACACTGCTCCATTTTCCACTGCACATAAACTCGGGACTGGTGGTG
Downstream sequence
TCGACGAACTCCCCACACAAGACTCCAAACCTGCTTCCTAAGCAACGTGACAAATGACTGTCCTAGTGAGTACATATTCCTGGGATCCAGGGAATTATAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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