Basic Information
VIS ID
TVIS44002711
Fusion event
HTLV-1-LOC105375371 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
79414912/79785596 (Hg38)
End
79414912/79785596 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105375371
Nearest miRNA
hsa-mir-10525/Upstream/3870327; hsa-mir-10399/Downstream/12418419;
Nearest TSS
ENST00000635602/Upstream/332022; ENST00000442586/Downstream/348359;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/331062, chr7-CpG: 135/Downstream/348881
Nearby gene
MIR548M(No orient, 14306)
Upstream sequence
ATATCATTCCAAGCCAGGCACTGTGTTAGAGAACTAAGTGAGAGGAAAATAATGAAAGGGTTTGCTTGCCATTATAATGAGTCAGGGATTCAATATCTTC
Downstream sequence
TGAACAGTTAAAGGTTATAGGTATGAGATAAACATTCAGACACATGCTTTTGAGTTACATTATGAAACAAGCATAAAGAAAGAAAGGCTGGCTAAGAAAT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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