Basic Information
VIS ID
TVIS44002738
Fusion event
HTLV-1-ITLN1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
160848832/160879042 (Hg38)
End
160848832/160879042 (Hg38)
Orient
-
Location type
Intronic
Target gene
ITLN1
Nearest miRNA
hsa-mir-101-1/Upstream/978963; hsa-mir-1182/Downstream/348144;
Nearest TSS
ENST00000473358/Upstream/16187; ENST00000356006/Downstream/2479;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/76879, chr1-CpG: 41/Downstream/141886
Upstream sequence
GGAAAACAACACCTGTGTTTCTCAAGGAATCTCAGCTCTAAAGACTTCTACACAATGTTTCAGCACACAAGCCTCACCCCAGCTCCAAGCGATTGAGTGT
Downstream sequence
TTTCTCACAAAGGCTGAACACCCAGTAATGGTTCTTTTGAAGCCTCACCCCTTGATTTTGGTCTTCAAAGTGACAGGATATGTATACCTGGACAAAAGTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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