Basic Information
VIS ID
TVIS44002777
Fusion event
HTLV-1-MIR4300HG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
81675310/81964268 (Hg38)
End
81675310/81964268 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
MIR4300HG
Nearest miRNA
hsa-mir-10392/Upstream/73432; hsa-let-7a-2/Downstream/4314065;
Nearest TSS
ENST00000527297/Upstream/1201442; ENST00000526154/Downstream/6726;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2523108, chr11-CpG: 25/Downstream/725275
Upstream sequence
TTAAATATAATATAATAACTCTTATGTTGATGAATGAAAGAAGTCAGATTTAGGGAAAATGAAAGAGCCTAGCTTGTGGCATTACTAGTCATCATGTGTA
Downstream sequence
ATTATGTTGATTGTTACTTCTGTGCaaattttcttaatcaacctctccttaacaaaacatcagagttaccattctccccataaagcatattagcagatgt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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