Basic Information
VIS ID
TVIS44002789
Fusion event
HTLV-1-ZNF37BP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
43033749/42538301 (Hg38)
End
43033749/42538301 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA10G
Target gene
ZNF37BP
Nearest miRNA
hsa-mir-1265/Upstream/6897049; hsa-mir-107/Downstream/459262;
Nearest TSS
ENST00000439456/Upstream/62673; ENST00000439913/Downstream/56366;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/60796, chr10-CpG: 67/Downstream/13835
Upstream sequence
caaggagtatctttgtggtattctctgtatttcctgaatttgaatgttgacctctcttgctaggttgggaaagttctcctggataatatcctgaagggtg
Downstream sequence
ttttccaacttggttcaattctccccgtcactttcaggtacaccaatcaaacatagatttggtcttttcacatagttccatatttcttggaagctttgtt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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