Basic Information
VIS ID
TVIS44002803
Fusion event
HTLV-1-SNX10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
26358829/26319209 (Hg38)
End
26358829/26319209 (Hg38)
Orient
-
Location type
Intronic
Target gene
SNX10
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-126-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-4795-3p ; hsa-mir-6509-5p ; hsa-mir-27b-5p ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-1252-5p ; hsa-mir-6830-3p ; hsa-mir-127-5p ; hsa-mir-331-5p ; hsa-mir-496 ; hsa-mir-3160-5p ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-6507-5p
Nearest miRNA
hsa-mir-1183/Upstream/369223; hsa-mir-10399/Downstream/850271;
Nearest TSS
ENST00000635602/Upstream/26155; ENST00000409367/Downstream/34848;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/26885, chr7-CpG: 124/Downstream/56917
Upstream sequence
TTGTACTTCTGTGGTCATAAGAGTGGCTTGTGAACAATGTCATGTCTGAAAAGCATTGGGAAGCTTGTTGAATTTAGATTTATTCACTGAATCAGTAGAC
Downstream sequence
GTAGATATTGTAGCAGTATCTTTCTAGGCTATTATCTCCTCCTTGAGGAACTCTGGTATATAACAACTGAAAATTAAATATACTTATGAAATGTTAGGAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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