Basic Information
VIS ID
TVIS44002812
Fusion event
HTLV-1-RPSAP35 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q26
Reference genome
GRCh37/hg19
Start
118334900/117413744 (Hg38)
End
118334900/117413744 (Hg38)
Orient
+
Location type
Intronic
Target gene
RPSAP35
Nearest miRNA
hsa-mir-12113/Upstream/2756890; hsa-mir-1305/Downstream/8093515;
Nearest TSS
ENST00000502981/Upstream/7578; ENST00000437514/Downstream/14652;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/328041, chr4-CpG: 80/Downstream/619511
Nearby gene
LINC01378(No orient, 14654)
Upstream sequence
ATCCAGCTGATGTGACTCATATCTTCTAGGAACACCAGCTATTCTGTGTTACTGAAATGGATTGCATTTACCATCCACACCTATTGCTGCATATACTTCA
Downstream sequence
TTCTCAGACTTTACTAAGCAGATCTAGGCAGCTTTCTTGGAGCCCCACGTTTTGCTGGGTGCTGATTACAGCATTGACCTCCCATGAAGGCATGTGATGT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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