Basic Information
VIS ID
TVIS44002827
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
85298641/84832297 (Hg38)
End
85298641/84832297 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1260a/Upstream/7566007; hsa-mir-1185-1/Downstream/9115929;
Nearest TSS
ENST00000550708/Upstream/917247; ENST00000554753/Downstream/407177;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/3298207, chr14-CpG: 45/Downstream/697853
Upstream sequence
TGGTGTGAACAGCCTAGAATGTACTAATTTTAGGTTAACAATGATAGGTTAATTTCCAAATTAAGACGGTAAAAATGATTACGCTTCAGAATGAAGCGTA
Downstream sequence
AAGTAGGATACCTCTGTGAAGTGTCTCATGAGCTTGGCATTGAGATTGGCAGATGTACCTTGATGTTCCCTTCAAATTTGGCTCTTCCTAACTTCCATCT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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