Basic Information
VIS ID
TVIS44002832
Fusion event
HTLV-1-NR2F2-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.2
Reference genome
GRCh37/hg19
Start
96776652/96233423 (Hg38)
End
96776652/96233423 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
NR2F2-AS1
Nearest miRNA
hsa-mir-10393/Upstream/3328948; hsa-mir-1302-10/Downstream/99838;
Nearest TSS
ENST00000557528/Upstream/743; ENST00000558885/Downstream/2362;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/906330, chr15-CpG: 151/Downstream/88229
Upstream sequence
cacctcagtcaccccatcctcaccaccacacccaatgctgggatgGGTTCCACTCCCAGGAGCAGGACAGCTGGGTCATGGGGCTCATGGATCAGTCTCC
Downstream sequence
ATCTGACTTCCCTGCGTTGACTATGAAGCACCCACCATGATGATGGTATCAGGTTCATAGCATGTGAATGgaagaatctggggctcaaagaggttaagtg
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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