Basic Information
VIS ID
TVIS44002835
Fusion event
HTLV-1-FAM20A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
66587369/68591228 (Hg38)
End
66587369/68591228 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAM20A
Nearest miRNA
hsa-mir-10226/Upstream/166680; hsa-mir-1250/Downstream/508314;
Nearest TSS
ENST00000595228/Upstream/32838; ENST00000591754/Downstream/568;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/78151, chr17-CpG: 135/Downstream/8749
Upstream sequence
gggagtctcactctgtggcccaggctggagtgcagtggcgcgatctcggctaactgcaagctccacctcctgggttcacgccattctcctgcctcagcct
Downstream sequence
cccgagtagctgggcgcccgccgccacgcccggttaatttttttgtatttttagtagagacggggtttcaccgtgttagccaggatggtctcaatctctt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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