Basic Information
VIS ID
TVIS44002839
Fusion event
HTLV-1-LOC105374317 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
21446428/21223556 (Hg38)
End
21446428/21223556 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105374317
Nearest miRNA
hsa-mir-3125/Upstream/1875051; hsa-mir-10b/Downstream/4105084;
Nearest TSS
ENST00000437798/Upstream/2371; ENST00000451511/Downstream/94104;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/179467, chr2-CpG: 256/Downstream/2161302
Nearby gene
TDRD15(No orient, 79190)
Upstream sequence
AAACCTGTCACATGCACACAGATGTAGATGCCTGGTGAAATCTTAGAAAATGTATTCACATTTATTCTCTGGCAGTAATATTCTTTTCACAAAGCATTCC
Downstream sequence
ACACTATGATAGCTGTATCATTAGTCTGATAATCTCAAGTTAATTCTCTGTTGCTTTTTATATGGTGTGCTCAGTGTATTGGTTTAGAGAAAAAGGCTGA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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