Basic Information
VIS ID
TVIS44002844
Fusion event
HTLV-1-LOC284930 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
48066937/47671188 (Hg38)
End
48066937/47671188 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA22A
Target gene
LOC284930
Nearest miRNA
hsa-let-7a-3/Upstream/1557420; hsa-mir-12114/Downstream/603176;
Nearest TSS
ENST00000624155/Upstream/39498; ENST00000438810/Downstream/15053;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/457616, chr22-CpG: 25/Downstream/538157
Upstream sequence
gagtttgaagccagcagatcacctgaggttggaagttcgagaccagcatgagcaacatggggaaaccccatctctactaaaaatacaaaattagtagggc
Downstream sequence
gtggtggcacatgcctgtaatcccagctactcgggaggctgaggcaggagaatcgcttgaacccgggaggcagaagttgcggtgagctgagatggcgcca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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