Basic Information
VIS ID
TVIS44002856
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
148270677/148573585 (Hg38)
End
148270677/148573585 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/1195464; hsa-mir-153-2/Downstream/2664836;
Nearest TSS
ENST00000635602/Upstream/1408; ENST00000307003/Downstream/16980;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/233829, chr7-CpG: 200/Downstream/124753
Nearby gene
C7orf33(No orient, 16980)
Upstream sequence
aaatgggatacatgtgcagaaggtgcaggtttgttacataggcatacgtgtgccatggtggtttgctgcacctattgacctgtcctctaagttccttccc
Downstream sequence
atcaccccccacccccaacaggccctagtgtaagttgttcccctctctgtgcccatatgttctcaatgttcaactcccacttatgagtgagaacatgagg
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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