Basic Information
VIS ID
TVIS44002878
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
85976034/85942428 (Hg38)
End
85976034/85942428 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12128/Upstream/24012; hsa-mir-11401/Downstream/1892164;
Nearest TSS
ENST00000527434/Upstream/6205; ENST00000599411/Downstream/39322;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/43092, chr16-CpG: 24/Downstream/5618
Nearby gene
IRF8(+19823) ;
Nearest cancer related gene
IRF8(TSG, +19823) ;
Upstream sequence
AGGAGTTTTGACACAACCAAGATGCCCTTCATTTAGCAGCTATGCAAGACGTTCGCTAGAAAGTGAACATCTTTTCAAAAGCCGAGGAGCGTGGGTTTTG
Downstream sequence
TGCTCTGTAAAGGTctgcgtgggctggccctgctcatccaccccaacccctgattcctggctctctcttgtttccccttgctgtcctggctccaggcaca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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