Basic Information
VIS ID
TVIS44002881
Fusion event
HTLV-1-LOC105372058 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
30458769/32878805 (Hg38)
End
30458769/32878805 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA18A
Target gene
LOC105372058
Nearest miRNA
hsa-mir-1-2/Upstream/2579845; hsa-mir-122/Downstream/2712932;
Nearest TSS
ENST00000575820/Upstream/43640; ENST00000580071/Downstream/75270;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/106466, chr18-CpG: 45/Downstream/561741
Nearby gene
CCDC178(No orient, 58597)
Upstream sequence
AAGGCCAAACAGAACTGTCCCACAGAAGCTATGTGGGGGTTGGGGCAGGGACAATGTGGGTCCTCTCTCTGCTCCATAGGCACAGAGATAATACAGTGCA
Downstream sequence
CTATGTTAATTAACACTTAAAGCTGATACAGACTAAAATAAACAAATGTGCACCCATTCTGGTTCCACTTCTAAGACCTCATCCCGAGACCATAACACAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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