Basic Information
VIS ID
TVIS44002884
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1698336/1698337 (Hg38)
End
1698336/1698337 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-1302-11/Upstream/884684; hsa-let-7e/Downstream/117822;
Nearest TSS
ENST00000633603/Upstream/45732; ENST00000586506/Downstream/49719;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/22199, chr19-CpG: 43/Downstream/362
Nearby gene
TCF3(-46008) ;
Nearest cancer related gene
TCF3(TSG, -46008) ;
Upstream sequence
tcagctatgattgcgccaccgcactccagcctgggtgacagagcgagaccctgtctcaagaaataagaagagaaggaaGTTGGTGGAGGACATTCCACGC
Downstream sequence
CAAGGAGCCCATGAGCCCCGGCTGGTGGTGCACGTGGAGCATTTGAAGTCACCACCAGTGACCCGGCCCAGGTGCCTCTGCAGTGGGACGGGAGGCCGGC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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