Basic Information
VIS ID
TVIS44002885
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
34268355/33777450 (Hg38)
End
34268355/33777450 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/13378096; hsa-let-7e/Downstream/1345250;
Nearest TSS
ENST00000633603/Upstream/92922; ENST00000590771/Downstream/18483;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/4449, chr19-CpG: 26/Downstream/708
Nearby gene
CHST8(+3941) ;
Upstream sequence
AGTAACACTGCCCCTACCTCCGGGGACTCCCAGCTGATGGGTACCATGACTCCTGAATGAGGAATAGGCAGGCGCCCCGGGGAGCAGGGTGTGGGGAGAG
Downstream sequence
GACTGTATGTTAGCCCCACTGCCCTGCCCGGGCCGGGGAGGGGGTGTGGGAGCCCTGAGCTGGGTTCTTCACACTGCCCTGGCCTGGCTGCTTGTTGGCC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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