Basic Information
VIS ID
TVIS44002906
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
9962754/9994714 (Hg38)
End
9962754/9994714 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-1/Upstream/1867653; hsa-let-7f-2/Downstream/1323900;
Nearest TSS
ENST00000429181/Upstream/27356; ENST00000466248/Downstream/20848;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2346, chrX-CpG: 252/Downstream/19759
Nearby gene
WWC3(+21041) ;
Upstream sequence
ggatcttattcattctattaataattatagttttgtacccgttaaccatcccactccccacccactacccttgccaggctctggtaaccatccttctact
Downstream sequence
ctctgtgaccatgagttcaattgttttgatttttatctcccacaaataagtgagaacattcaaagtctgtctttctgtacctggcttatttcacttaaca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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